HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide → N-(6-Acetyl-3-methoxy-2-methylphenyl)-4-(propan-2-yl)-1,3-thiazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(2-acetyl-5-methoxyphenyl)-4-Isopropyl-2-Thiazolecarboxamide | HCID 20773655 | — |
| Reactant | 2'-Amino-3'-methyl-4'-methoxyacetophenone | HCID 25067316 | — |
| Reactant | 4-(Propan-2-yl)-1,3-thiazole-2-carbonyl chloride | HCID 57578796 | — |
| Product | N-(6-Acetyl-3-methoxy-2-methylphenyl)-4-(propan-2-yl)-1,3-thiazole-2-carboxamide | HCID 53482122 | 66% |
Reaction Steps
Compound 217b was synthesized from compound 201b and compound 214 as a beige solid in 66% yield, according to the procedure as described for compound 217a. MS (ESI, EI+): m/z=333 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09353100B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-66dadf606df943edb33bcade3bed10cc |
| Source note | uspto-grants-2016_05 |