HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → methyl 1-methyl-1H-pyrazole-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Methyl pyrazolo[1,5-a]pyridine-3-carboxylate carbamate | HCID 90419258 | — |
| Product | methyl 1-methyl-1H-pyrazole-3-carboxylate | HCID 7017175 | — |
Reaction Steps
To a solution of compound 1 (1.26 g, 10 mmol) in methanol (30 mL) was added sulfuric acid (0.5 mL). The resulting mixture was refluxed for 2 h and the solvent was evaporated. The residue was dissolved in EA (60 mL) and washed with brine, dried over Na2SO4. Then filtered and concentrated to give the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09353104B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-f3dbd1453946429894a2b8a33962d031 |
| Source note | uspto-grants-2016_05 |