methyl 1-methyl-1H-pyrazole-3-carboxylate → 1-Methyl-1H-pyrazole-3-carboxamide

HRID 530812Notes

Reaction equation

HRID 530812 reaction equation
[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([C:7]([O:9]C)=O)=[N:3]1.[NH3:11].O>>[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([C:7]([NH2:11])=[O:9])=[N:3]1

Participants

3

Reactant 2

HCID 7017175methyl 1-methyl-1H-pyrazole-3-carboxylateHCID 12896473Azane;hydrate

Product 1

HCID 134645861-Methyl-1H-pyrazole-3-carboxamide

Procedure

A solution of methyl 1-methyl-1H-pyrazole-3-carboxylate (1.1 g, 7.9 mmol) in NH3.H2O (10 mL) was stirred for 2 h at room temperature. The solvent was evaporated to give the crude product which was used for the next step without further purification.

Workup

  1. customThe solvent was evaporated

Sources & evidence

ORD record
ord-c756c510a23a4298a52158dbfa1c4385
Source dataset
uspto-grants-2016_05
Patent number
US09353104B2

Reaction notes

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