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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 530840Generated: October 30, 2026

Hydrochloric Acid → Hydrochloric Acid

https://huagongshe.com/reaction/530840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTert-butyl 3-(2-fluorobenzyl)-3-hydroxycyclohexylcarbamateHCID 67983409—
Solvent1,4-DioxaneHCID 31275—
ProductHydrochloric AcidHCID 313—
Product3-Amino-1-(2-fluorobenzyl)cyclohexanolHCID 67983841—

Reaction Steps

tert-Butyl 3-(2-fluorobenzyl)-3-hydroxycyclohexylcarbamate was stirred in a solution of HCl in dioxane (4 M) at room temperature for one hour. The product, HCl salt of 3-amino-1-(2-fluorobenzyl)cyclohexanol, was obtained after evaporation of solvent.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09351965B2
Source datasetuspto-grants-2016_05
ORD IDord-1ba40411662c4db29ecd26b07214ba60
Source noteuspto-grants-2016_05