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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 530850Generated: October 31, 2026

3-(Tert-butoxycarbonylamino)-1-(3-fluorophenoxy)cyclohexanecarboxylic acid → 3-Amino-1-(3-fluorophenoxy)cyclohexanecarboxylic acid

https://huagongshe.com/reaction/530850

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Tert-butoxycarbonylamino)-1-(3-fluorophenoxy)cyclohexanecarboxylic acidHCID 67983401—
SolventTrifluoroacetic acidHCID 6422—
Product3-Amino-1-(3-fluorophenoxy)cyclohexanecarboxylic acidHCID 67983650—

Reaction Steps

A reaction mixture of 3-(tert-butoxycarbonylamino)-1-(3-fluorophenoxy)cyclohexanecarboxylic acid in TFA (neat) was stirred at room temperature for 10 minutes. The product, 3-amino-1-(3-fluorophenoxy)cyclohexanecarboxylic acid, was obtained after purification by reverse phase HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09351965B2
Source datasetuspto-grants-2016_05
ORD IDord-9a95235d3e1a44adaf80467cbb98f3f5
Source noteuspto-grants-2016_05