Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 530866Generated: October 30, 2026

Trifluoroacetic acid → HCID 57410789, compound

https://huagongshe.com/reaction/530866

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67985234HCID 67985234—
CatalystTriethylsilaneHCID 12052—
ProductHCID 57410789HCID 57410789—

Reaction Steps

Trifluoroacetic acid (5 mL) was added to N-(-3-((1H-indazol-1-yl)methyl)-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1-trityl-1H-indazole-5-carboxamide (0.1 mmol). The reaction was stirred at room temperature for 30 minutes. Triethylsilane (1 drop) was added to the reaction and stirred for an additional 5 minutes. The crude product purified using prep HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09351965B2
Source datasetuspto-grants-2016_05
ORD IDord-6e9c90f564d0491eaca7ba95db41986b
Source noteuspto-grants-2016_05