反应详情

In a flask, methyl 3-aminocyclohexanecarboxylate (3.86 g, 19.94 mmol) was dissolved in dichloromethane (80 mL). Benzophenone imine (3.33 mL, 19.94 mmol) was added to the reaction, and the reaction was stirred at room temperature for 24 hrs. Upon completion, the reaction was concentrated and triturated with diethyl ether. The suspension was filtered. This trituration process was done twice. The remaining filtrate was concentrated and progressed to the next step without further purification.

1. concentrationUpon completion, the reaction was concentrated
2. customtriturated with diethyl ether
3. filtrationThe suspension was filtered
4. concentrationThe remaining filtrate was concentrated
5. customprogressed to the next step without further purification