HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Benzenesulfonamide, 4-methyl-N-phenyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | Benzenesulfonamide, 4-methyl-N-phenyl- | HCID 2456 | — |
Reaction Steps
Aniline (5 g, 54 mmol) was reacted with p-toluenesulfochloride (15 g, 78 mmol) in 10% sodium hydroxide solution under standard conditions (Vogel, Id, at p. 1275). The product (8.9 g, 36 mmol) was twice recrystallized from ethanol; the melting point was 102°-103° C., yield, 67%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618726 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-da65fb542baf407499701a08080f5181 |
| Source note | uspto-grants-1997_04 |