4,5-Dicyclopropyl-2-ethoxybenzenemethanol → 4,5-Dicyclopropyl-2-ethoxybenzaldehyde

Participants

Reaction Conditions

Reaction Steps

Manganese dioxide (8.50 g) was added at room temperature to a toluene (50 mL) solution of (4,5-dicyclopropyl-2-ethoxyphenyl)methanol (2.84 g) in a nitrogen atmosphere, and the mixture was stirred at 80° C. for 1 hour. The reaction mixture was filtered through celite, and then, the filtrate was concentrated. The obtained residue was purified by silica gel column chromatography (hexane/ethyl acetate) to obtain the title compound (2.68 g).

Provenance & Evidence