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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 531237Generated: October 27, 2026

3-Bromo-6-chloro-2-methylpyridine → 3-Bromo-2-(bromomethyl)-6-chloropyridine

https://huagongshe.com/reaction/531237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-6-chloro-2-methylpyridineHCID 14866674—
Reactant(4S,5R)-3-{[5-Bromo-2-(methylthio)pyrimidin-4-yl]methyl}-4-methyl-5-[3-(trifluoromethoxy)phenyl]-1,3-oxazolidin-2-oneHCID 90009127—
Product3-Bromo-2-(bromomethyl)-6-chloropyridineHCID 23249915—

Reaction Steps

The preparation of this precursor from commercially available 6-chloro-3-bromo-2-methylpyridine has been described previously in WO2007081569, INTERMEDIATE 9 Step B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09353101B2
Source datasetuspto-grants-2016_05
ORD IDord-36a584ced05f462dbfd4a50b14454e19
Source noteuspto-grants-2016_05