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HRID53130

反应详情

EQUATION

反应方程式

HRID 53130 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)NC(=O)CN1C(=O)C(N=[N+]=[N-])CC(c2ccccc2)c2ccccc21
HCID15203363

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)NC(=O)CN1C(=O)C(N)CC(c2ccccc2)c2ccccc21
HCID15203365

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A solution of 5.80 grams (14.3 retool) N-tert-butyl-2-(3-azido-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-(1)benzazepin-1-yl) ethanoic acid amide in 70 mL ethanol (with methylene chloride as necessary to aid dissolution) was treated with 600 mg 10% palladium on carbon under hydrogen (42 to 39 psi) for 20.5 hours. The reaction was filtered through Celite® with ethanol and methylene chloride and evaporated to a foam, 5.44 grams (100%).

WORKUP

后处理

  1. filtrationThe reaction was filtered through Celite® with ethanol and methylene chloride
  2. customevaporated to a foam, 5.44 grams (100%)