HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Isopropylpyridine → 1-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Isopropylpyridine | HCID 69523 | — |
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine | HCID 13172079 | 85% |
Reaction Steps
A mixture of isopropylpyridine (2.1 g, 17.75 mmol) and m-CPBA (5.0 g, 1.3 eq.) in CH2Cl2 was stirred overnight at room temperature. Then, the reaction mixture was diluted with CH2Cl2 (twice the volume) and successively washed with aqueous sodium bicarbonate (twice) and brine, dried (Na2SO4) and evaporated to give 2.0 g (85%) of the title compound 104.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09353103B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-7e7df1dbeefb4f51beed96520078dffc |
| Source note | uspto-grants-2016_05 |