4-(Benzyloxy)-2-chloro-7-methoxy-8-methylquinoline → HCID 178487708, 화합물

HRID 531371노트

반응식

HRID 531371 반응식
C([O:8][C:9]1[C:18]2[C:13](=[C:14]([CH3:21])[C:15]([O:19][CH3:20])=[CH:16][CH:17]=2)[N:12]=[C:11](Cl)[CH:10]=1)C1C=CC=CC=1.[C:23]([C:27]1[CH:31]=[CH:30][NH:29][N:28]=1)([CH3:26])([CH3:25])[CH3:24].OC1C2C(=C(C)C(OC)=CC=2)N=C(N2C=CC(C(C)C)=N2)C=1>>[OH:8][C:9]1[C:18]2[C:13](=[C:14]([CH3:21])[C:15]([O:19][CH3:20])=[CH:16][CH:17]=2)[N:12]=[C:11]([N:29]2[CH:30]=[CH:31][C:27]([C:23]([CH3:26])([CH3:25])[CH3:24])=[N:28]2)[CH:10]=1

참가 물질

4

반응물 3

HCID 576079364-(Benzyloxy)-2-chloro-7-methoxy-8-methylquinolineHCID 178441177HCID 178441177, 화합물HCID 178487709HCID 178487709, 화합물

생성물 1

HCID 178487708HCID 178487708, 화합물

실험 절차

The title compound was prepared from 4-benzyloxy-2-chloro-7-methoxy-8-methylquinoline (63) and 3-tert-butylpyrazole following the procedure reported for the preparation of 4-hydroxy-2-(3-isopropylpyrazol-1-yl)-7-methoxy-8-methylquinoline (64): m/z=312 (M+H)+.

출처 및 근거

ORD 기록
ord-8e9b585db79e4f3eb5a9b6112b2bc6d2
출처 데이터셋
uspto-grants-2016_05
특허 번호
US09353103B2

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