Water → Aluminum tris(3-(diethoxyphosphoryl)propanoate)

HRID 531406Notes

Reaction equation

[CH2:1]([O:3][P:4]([CH2:9][CH2:10][C:11]([OH:13])=[O:12])([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].O.O.[OH-].[Al+3:17].[OH-].[OH-]>CC(C)=O>[CH2:7]([O:6][P:4]([CH2:9][CH2:10][C:11]([O-:13])=[O:12])([O:3][CH2:1][CH3:2])=[O:5])[CH3:8].[CH2:7]([O:6][P:4]([CH2:9][CH2:10][C:11]([O-:13])=[O:12])([O:3][CH2:1][CH3:2])=[O:5])[CH3:8].[CH2:7]([O:6][P:4]([CH2:9][CH2:10][C:11]([O-:13])=[O:12])([O:3][CH2:1][CH3:2])=[O:5])[CH3:8].[Al+3:17]

Participants

Conditions

Temperature: 90 °C

Procedure

Use as a reaction vessel a 500 milliliter (mL) single neck round bottomed flask fitted with a condenser with a nitrogen inlet. Charge the vessel with 3-(diethyoxyphosphoryl)propanoic acid (20.30 g) followed by the addition of water (150 mL) and aluminum hydroxide monohydrate (2.709 g). Heat the resulting solution to 90° C. and hold at that temperature for eight hours. Remove the water using a rotovap to leave behind a solid material. Add 100 mL of acetone and isolate the solid by vacuum filtration using a Buchner funnel and wash with acetone (100 mL). Transfer the solid product to a glass bottle and place in a vacuum oven to dry overnight. The yield of the solid product, aluminum tris(3-(diethoxyphosphoryl)propanoate), is 12.45 g.

Workup

customUse as a reaction vessel a 500 milliliter (mL) single neck round bottomed flask fitted with a condenser with a nitrogen inlet
customRemove the water using a rotovap
customto leave behind a solid material
customisolate the solid
filtrationby vacuum filtration
washwash with acetone (100 mL)
customto dry overnight

Sources & evidence

ORD record: ord-d2d2418c20b5407db9b299a8703ce8d6
Source dataset: uspto-grants-2016_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09353246B2

Reaction notes

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