Lithium Hydroxide → HCID 118523986, compound

Participants

Reaction Steps

Using similar reaction conditions as described in step-iii of example-1, tert-butyl 4-(4-(3-(3,5-dimethyl-1-(3-methylbenzyl)-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)piperazine-1-carboxylate (90 mg, 0.1 mmol) was hydrolyzed by lithium hydroxide (9 mg, 0.3 mmol), THF/Methanol/water (1/1/0.5 ml) to afford 20 mg (29% yield) of the titled compound. MS: m/z=577.2 (M+1).

Provenance & Evidence