HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-chloro-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido[5,4-d]pyrimidine → 4-(1-Pyrrolidinyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-chloro-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido[5,4-d]pyrimidine | HCID 12817020 | — |
| Reactant | 2-(4-pyrrolidino-piperidin-1-yl)-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido [5,4-d]pyrimidine | HCID 54484534 | — |
| Product | 4-(1-Pyrrolidinyl)piperidine | HCID 78703 | 57% |
Reaction Steps
2-(4-pyrrolidino-piperidin-1-yl)-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido [5,4-d]pyrimidine From 2-chloro-8-(N-benzyl-N-methyl-amino)-4-morpholino-pyrimido[5,4-d]pyrimidine and 4-pyrrolidino-piperidine Yield: 57% of theory, Melting point: 131°-134° C. C27H36N8O (488.64)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618814 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-6d337ea80a0048059806516a511c0bdf |
| Source note | uspto-grants-1997_04 |