HCID 67709062, compound → HCID 54425938, compound

HRID 53162Notes

Reaction equation

HRID 53162 reaction equation
CO[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1OC)[CH2:9][N:8]([C:15]1[C:20]3[N:21]=[C:22]([N:31]4[CH2:36][CH2:35][C:34](=[O:37])[CH2:33][CH2:32]4)[N:23]=[C:24]([N:25]4[CH2:30][CH2:29][O:28][CH2:27][CH2:26]4)[C:19]=3[N:18]=[CH:17][N:16]=1)[CH2:7]C2>C(OCC)(=O)C.C1CCCCC1>[CH2:9]([N:8]([C:15]1[C:20]2[N:21]=[C:22]([N:31]3[CH2:32][CH2:33][C:34](=[O:37])[CH2:35][CH2:36]3)[N:23]=[C:24]([N:25]3[CH2:26][CH2:27][O:28][CH2:29][CH2:30]3)[C:19]=2[N:18]=[CH:17][N:16]=1)[CH3:7])[C:10]1[CH:11]=[CH:12][CH:3]=[CH:4][CH:5]=1

Participants

3

Reactant 1

HCID 67709062HCID 67709062, compound

Product 1

HCID 54425938HCID 54425938, compound

Reagents, catalysts & solvents 1

HCID 21867204Cyclohexane ethylacetateSolvent

Procedure

8-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-(4-oxo-piperidin-1-yl) -4-morpholino-pyrimido[5,4-d]-pyrimidine Rf value: 0.09 (silica gel; ethyl acetate/cyclohexane =2:1)

Sources & evidence

ORD record
ord-4657ff7fc17e4676b250fdf997c417ba
Source dataset
uspto-grants-1997_04
Patent number
US05618814

Reaction notes

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