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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 531712Generated: October 31, 2026

HCID 118523895, compound → HCID 118523985, compound

https://huagongshe.com/reaction/531712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 118523895HCID 118523895—
SolventTrifluoroacetic acid methylene chlorideHCID 21863450—
ProductHCID 118523985HCID 118523985102.2%

Reaction Steps

Using similar reaction conditions as described in step-ii of example-7, tert-butyl 4-(4-(3-(1-phenethyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)piperazine-1-carboxylate (200 mg, 0.284 mmol) was deprotected in TFA/DCM (2/5 ml) to afford 175 mg (86.2% yield) of the titled compound. MS: m/z=603.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09353107B2
Source datasetuspto-grants-2016_05
ORD IDord-8f532e78b26641d0a1d6838ac97e00a0
Source noteuspto-grants-2016_05