HuagongsheHuagongshe Chemistry Print Report · For research reference only
2h-Pyrrolo[2,3-b]pyridin-2-one,5-acetyl-1,3-dihydro-1,3,3-trimethyl- → 1,3-dihydro-1-methyl-5-acetyl-2H-pyrrolo[2,3-b]pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2h-Pyrrolo[2,3-b]pyridin-2-one,5-acetyl-1,3-dihydro-1,3,3-trimethyl- | HCID 10608854 | — |
| Reactant | 5-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one | HCID 15296268 | — |
| Product | 1,3-dihydro-1-methyl-5-acetyl-2H-pyrrolo[2,3-b]pyridin-2-one | HCID 10845351 | 84% |
Reaction Steps
By proceeding in the same manner as for the synthesis of the compound of Example 12, but replacing the 1,3-dihydro-1,3,3-trimethyl-5-bromo-2H-pyrrolo[2,3-b]pyridin-2-one with 1,3-dihydro-1-methyl-5-bromo-2H-pyrrolo[2,3-b]pyridin-2-one, the title compound is obtained in a yield of 84%. ##STR60##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618819 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-ef37cb156e19453faa4d71aeba15b866 |
| Source note | uspto-grants-1997_04 |