HCID 10448929, compound → HCID 19079279, compound

HRID 53176Notes

Reaction equation

HRID 53176 reaction equation
CN1C2=NC=C(C[N:12]3[CH2:17][CH2:16][N:15]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[CH2:14][CH2:13]3)C=C2OC1=O.[CH3:25][N:26]1[C:30]2=[N:31][CH:32]=[C:33]([C:35](=[O:38])[CH2:36]Br)[CH:34]=[C:29]2[O:28][C:27]1=[O:39].CN1C2=NC=C(CBr)C=C2OC1=O>>[CH3:25][N:26]1[C:30]2=[N:31][CH:32]=[C:33]([C:35](=[O:38])[CH2:36][N:12]3[CH2:17][CH2:16][N:15]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[CH2:14][CH2:13]3)[CH:34]=[C:29]2[O:28][C:27]1=[O:39]

Participants

4

Reactant 3

HCID 10448929HCID 10448929, compoundHCID 19079296HCID 19079296, compoundHCID 19079305HCID 19079305, compound

Product 1

HCID 19079279HCID 19079279, compound

Procedure

The method of operation is the same as that used for the synthesis of the compound of Example 16, 3-methyl-6-(bromoacetyl)oxazolo[4,5-b]pyridin-2(3H)-one from Preparation 17 being used instead of 3-methyl-6-(bromomethyl)oxazolo[4,5-b]pyridin-2(3H)-one. The yield obtained is 84%. ##STR70##

Workup

  1. customThe yield obtained

Sources & evidence

ORD record
ord-55afbf1fd7a040f5abb4ab4db02282e7
Source dataset
uspto-grants-1997_04
Patent number
US05618819

Reaction notes

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