Hydrochloric Acid → 3-(1-(3-methylbenzyl)-1H-pyrazol-4-yl)-5-(6-(piperazin-1-yl)pyridin-3-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine hydrochloride

Participants

Reaction Steps

Using similar reaction conditions as described in step-ii of example-7, tert-butyl 4-(5-(3-(1-(3-methylbenzyl)-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-2-yl)piperazine-1-carboxylate (200 mg, 0.284 mmol) was deprotected in HCl in ether/methanol (2/3 ml) to afford 120 mg (66% yield) of the titled compound. MS: m/z=605.2 (M+1).

Provenance & Evidence