Diisopropylethylamine → HCID 90030678, compound

Participants

Reaction Steps

Using similar reaction conditions as described in step-i of example-82A, 3-(1-(3-fluorobenzyl)-1H-pyrazol-4-yl)-5-(5-(piperazin-1-yl)pyridin-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine (100 mg. 0.164 mmol) was alkylated using (S)-2-methyloxirane (18 mg, 0.329 mmol), DIPEA (58 μL, 0.329 mmol) and ethanol (10 mL) to get 100 mg (91.7%) of the titled compound.

Provenance & Evidence