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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 531803Generated: October 30, 2026

HCID 90031578, compound → HCID 118524106, compound

https://huagongshe.com/reaction/531803

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 90031578HCID 90031578—
SolventHydrochloric AcidHCID 313—
SolventDiethyl EtherHCID 3283—
ProductHCID 118524106HCID 118524106161.1%

Reaction Steps

Using similar reaction conditions as described in step-ii of example-7, tert-butyl 4-(5-(3-(1-(3-chlorobenzyl)-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyridin-2-yl)piperazine-1-carboxylate (185 mg, 0.25 mmol) was deprotected in HCl in ether (10 ml) to afford 133 mg (78.8% yield) of the titled compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09353107B2
Source datasetuspto-grants-2016_05
ORD IDord-17aa8db992b24caeb38865d229917af9
Source noteuspto-grants-2016_05