2-Bromoethanol → HCID 90031775, compound

Participants

Reaction Steps

Using the same reaction conditions as described in step-ii of example-35, 3-(1-(3-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl)-5-(3-(piperazin-1-yl)phenyl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine (70 mg, 0.104 mmol) was alkylated with 2-bromoethanol (13 mg, 0.104 mmol) using potassium carbonate (73 mg, 0.522 mmol), DMF (2 ml) to yield 60 mg (84.5%) of the titled compound. MS: m/z=679.3 (M+1).

Provenance & Evidence