3-(5-Bromo-thiazol-2-yl)-1,1-dicyclohexyl-urea → HCID 57883902, compound
Reaction equation
Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:22])[N:9]([CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH3:23][O:24][C:25](=[O:33])[C:26]1[CH:31]=[CH:30][CH:29]=[N:28][C:27]=1[SH:32]>>[CH3:23][O:24][C:25](=[O:33])[C:26]1[CH:31]=[CH:30][CH:29]=[N:28][C:27]=1[S:32][C:2]1[S:6][C:5]([NH:7][C:8]([N:9]([CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)=[O:22])=[N:4][CH:3]=1Participants
3
Procedure
Prepared as described in general procedure (E) using 3-(5-bromo-thiazol-2-yl)-1,1-dicyclohexyl-urea and 2-mercaptonicotinic acid methylester.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-781f6daed16545c2a0fa00a8308a3759
- Source dataset
- uspto-grants-2014_10
- Patent number
- USRE045183E1
Reaction notes
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