3-(5-Bromothiazol-2-yl)-1-cyclohexyl-1-(4-methylcyclohexyl)-urea → HCID 57883563, compound

HRID 531930Notes

Reaction equation

HRID 531930 reaction equation
Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[CH:10]2[CH2:15][CH2:14][CH:13]([CH3:16])[CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH2:24]([O:26][C:27]([C:29]1[N:30]([CH3:35])[C:31]([SH:34])=[N:32][CH:33]=1)=[O:28])[CH3:25]>>[CH2:24]([O:26][C:27]([C:29]1[N:30]([CH3:35])[C:31]([S:34][C:2]2[S:6][C:5]([NH:7][C:8]([N:9]([CH:17]3[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]3)[CH:10]3[CH2:15][CH2:14][CH:13]([CH3:16])[CH2:12][CH2:11]3)=[O:23])=[N:4][CH:3]=2)=[N:32][CH:33]=1)=[O:28])[CH3:25]

Participants

3

Reactant 2

HCID 578835793-(5-Bromothiazol-2-yl)-1-cyclohexyl-1-(4-methylcyclohexyl)-ureaHCID 178469865HCID 178469865, compound

Product 1

HCID 57883563HCID 57883563, compound

Procedure

Prepared as described in general procedure (E) from 3-(5-bromothiazol-2-yl)-1-cyclohexyl-1-(4-methylcyclohexyl)-urea (Example 242) and 2-mercapto-3-methyl-3H-imidazole-4-carboxylic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2d3837d2e1c64eefb75a25f62c4577ca
Source dataset
uspto-grants-2014_10
Patent number
USRE045183E1

Reaction notes

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