HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentanecarbonyl chloride → HCID 57883570, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentanecarbonyl chloride | HCID 78284 | — |
| Reactant | HCID 86611203 | HCID 86611203 | — |
| Product | HCID 57883570 | HCID 57883570 | 40% |
Reaction Steps
Prepared as described in general procedure (N) using 3-[5-(4-ethanesulfonyl-piperazin-1-ylmethyl)-thiazol-2-yl]-1-(4-methyl-cyclohexyl)-1-piperidin-4-yl-urea hydrochloride (48 mg, 0.078 mmol), TEA (24 μL, 0.17 mmol) and cyclopentane carbonylchloride (11 μL, 0.086 mmol) and to afford 19 mg (40%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE045183E1 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-97f1938b86d443028aa86a6779052248 |
| Source note | uspto-grants-2014_10 |