HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzoyl chloride → HCID 57883808, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | HCID 86611203 | HCID 86611203 | — |
| Product | HCID 57883808 | HCID 57883808 | 86.1% |
Reaction Steps
Prepared as described in general procedure (N) using 3-[5-(4-ethanesulfonyl-piperazin-1-ylmethyl)-thiazol-2-yl]-1-(4-methyl-cyclohexyl)-1-piperidin-4-yl-urea hydrochloride (46 mg, 0.075 mmol), TEA (26 μL, 0.19 mmol) and 4-fluorobenzoyl chloride (10 μL, 0.083 mmol) and to afford 41 mg (86%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE045183E1 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-63b23f1ac3e6492987ab26419e83c88e |
| Source note | uspto-grants-2014_10 |