2-(Methylsulfonyl)ethanamine → HCID 57883492, compound

HRID 532008Notes

Reaction equation

HRID 532008 reaction equation
[CH:1]1([N:7]([CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[C:8](=[O:18])[NH:9][C:10]2[S:11][C:12]([C:15]([OH:17])=O)=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:25][CH2:26][CH2:27][S:28]([CH3:31])(=[O:30])=[O:29]>>[CH3:31][S:28]([CH2:27][CH2:26][NH:25][C:15]([C:12]1[S:11][C:10]([NH:9][C:8]([N:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[CH:19]2[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]2)=[O:18])=[N:14][CH:13]=1)=[O:17])(=[O:30])=[O:29]

Participants

3

Reactant 2

HCID 43405612-(Methylsulfonyl)ethanamineHCID 114054472-(3,3-Dicyclohexylureido)thiazole-5-carboxylic acid

Product 1

HCID 57883492HCID 57883492, compoundYield 75%

Procedure

Prepared in 75% yield (170 mg) as described in general procedure (H) from 2-(3,3-dicyclohexylureido)thiazole-5-carboxylic acid (175 mg, 0.5 mmol) and 2-aminoethylmethylsulfone (HCl salt, 80 mg, 0.5 mmol).

Workup

  1. customPrepared in 75% yield (170 mg)

Sources & evidence

ORD record
ord-8e7d504eac4642d69f5feaf27ee5a8f0
Source dataset
uspto-grants-2014_10
Patent number
USRE045183E1

Reaction notes

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