4-(3-Chloropropyl)morpholine → HCID 178461377, compound

HRID 532039Notes

Reaction equation

HRID 532039 reaction equation
[CH:1]1([N:7]([C@H:19]2[CH2:24][CH2:23][C@H:22]([CH3:25])[CH2:21][CH2:20]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16]C#N)=[CH:14][N:15]=2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.SC[C@@H]([C@@H](CS)O)O.Cl[CH2:35][CH2:36][CH2:37][N:38]1[CH2:43][CH2:42][O:41][CH2:40][CH2:39]1>>[CH:1]1([N:7]([C@H:19]2[CH2:20][CH2:21][C@H:22]([CH3:25])[CH2:23][CH2:24]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH2:35][CH2:36][CH2:37][N:38]3[CH2:43][CH2:42][O:41][CH2:40][CH2:39]3)=[CH:14][N:15]=2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 958344-(3-Chloropropyl)morpholineHCID 439352DithioerythritolHCID 178461390HCID 178461390, compound

Product 1

HCID 178461377HCID 178461377, compound

Procedure

Prepared as described in general procedure (H) using 1-cyclohexyl-1-(trans-4-methyl-cyclohexyl)-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 4-(3-chloropropyl) morpholine

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fbb27b3e883845fa8361768b7fe4e7bb
Source dataset
uspto-grants-2014_10
Patent number
USRE045183E1

Reaction notes

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