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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 532063Generated: November 1, 2026

Dimethylsulphamoyl chloride → HCID 178473161, compound

https://huagongshe.com/reaction/532063

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylsulphamoyl chlorideHCID 83372—
ReactantHCID 178473158HCID 178473158—
ProductHCID 178473161HCID 178473161—
ProductHCID 178486169HCID 178486169—

Reaction Steps

{2-[3-(1-Dimethylsulfamoyl-piperidin-4-yl)-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was prepared in a similar manner to Example 554 using {2-[3-(trans-4-methyl-cyclohexyl)-3-piperidin-4-yl-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester and dimethylsulfamoyl chloride. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE045183E1
Source datasetuspto-grants-2014_10
ORD IDord-e5a2d001ffcc4638bdff55a13f20ca3c
Source noteuspto-grants-2014_10