HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → Dimethyl 3-(2-methoxy-2-oxoethyl)pentanedioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 3(Methoxycarbonylmethylene)glutaric acid dimethylester | HCID 12053850 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Dimethyl 3-(2-methoxy-2-oxoethyl)pentanedioate | HCID 19038603 | — |
Reaction Steps
3-(methoxycarbonylmethylene)glutaric acid dimethylester (89 g, 267 mmol) in methanol (200 ml) was shaken with (10% palladium on charcoal: 50% water) (9 g) under an atmosphere of hydrogen gas (3.5 bar) for (30 h). The solution was filtered through kieselguhr and concentrated in vacuo to give 3-(methoxycarbonylmethyl)glutaric acid dimethylester as an oil, yield (84.9 g, 94%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08852550B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-1def1c3b86754cae9b14e916e672c4da |
| Source note | uspto-grants-2014_10 |