HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetyl-6-(3-hydroxy-2-propynyl)pyridine → 2-Acetyl-6-(3-hydroxypropyl)-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetyl-6-(3-hydroxy-2-propynyl)pyridine | HCID 19082010 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2-Acetyl-6-(3-hydroxypropyl)-pyridine | HCID 19082007 | 84.6% |
Reaction Steps
A suspension of 1.3 g of 2-acetyl-6-(3-hydroxy-2-propynyl)pyridine and 0.5 g of 10% Pd/C in 50 ml of ethyl acetate was hydrogenated at 50 psi (H2) overnight. The mixture was filtered and the filtrate was concentrated in vacuo to yield 1.1 g (84.6%) of 2-acetyl-6-(3-hydroxypropyl)-pyridine, as a yellow oil (crude).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618821 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-3220137bd9a74e25a876712979ff80b5 |
| Source note | uspto-grants-1997_04 |