Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate → HCID 178499247, compound

HRID 532258Notes

Reaction equation

HRID 532258 reaction equation
[CH3:1][O:2][C:3]([C:5]1[S:14][C:8]2[N:9]=[CH:10][N:11]=[C:12](Cl)[C:7]=2[C:6]=1[CH3:15])=[O:4].[NH2:16][C:17]1[C:18]([OH:23])=[N:19][CH:20]=[CH:21][CH:22]=1>>[OH:23][C:18]1[C:17]([NH:16][C:12]2[C:7]3[C:6]([CH3:15])=[C:5]([C:3]([O:2][CH3:1])=[O:4])[S:14][C:8]=3[N:9]=[CH:10][N:11]=2)=[CH:22][CH:21]=[CH:20][N:19]=1

Participants

3

Reactant 2

HCID 2759834Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylateHCID 178418824HCID 178418824, compound

Product 1

HCID 178499247HCID 178499247, compound

Procedure

Prepared analogously to example III using 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester and 3-amino-2-hydroxypyridine

Workup

  1. customPrepared analogously to example III

Sources & evidence

ORD record
ord-e042782ce30f45529865e519a5baad9f
Source dataset
uspto-grants-2014_10
Patent number
US08853193B2

Reaction notes

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