HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Fluoropropoxy)-3-nitropyridine → 2-(2-Fluoropropoxy)pyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Fluoropropoxy)-3-nitropyridine | HCID 58413305 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(2-Fluoropropoxy)pyridin-3-amine | HCID 58413385 | — |
Reaction Steps
2-(2-fluoropropoxy)-3-nitropyridine (199.97 mg) was dissolved in a mixture of THF (10 ml) and methanol (5 ml). Pd/C (20 mg) was added and the mixture was hydrogenated at room temperature for 4 h and 3 bar. The mixture was concentrated in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853193B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-cc68b35ccd2f43699ae394ab4323f65f |
| Source note | uspto-grants-2014_10 |