(2,2-Difluorocyclopropyl)methanol → 2-((2,2-Difluorocyclopropyl)methoxy)-3-nitropyridine

HRID 532271Notes

Reaction equation

HRID 532271 reaction equation
[F:1][C:2]1([F:7])[CH2:4][CH:3]1[CH2:5][OH:6].F[C:9]1[C:14]([N+:15]([O-:17])=[O:16])=[CH:13][CH:12]=[CH:11][N:10]=1>>[F:1][C:2]1([F:7])[CH2:4][CH:3]1[CH2:5][O:6][C:9]1[C:14]([N+:15]([O-:17])=[O:16])=[CH:13][CH:12]=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 2761401(2,2-Difluorocyclopropyl)methanolHCID 27628172-Fluoro-3-nitropyridine

Product 1

HCID 584132352-((2,2-Difluorocyclopropyl)methoxy)-3-nitropyridine

Procedure

Prepared analogously to example XII.1 using (2,2-difluorocyclopropyl)methanol and 2-fluoro-3-nitro-pyridine

Sources & evidence

ORD record
ord-f422a726487a4367a4404f2c6bedcf71
Source dataset
uspto-grants-2014_10
Patent number
US08853193B2

Reaction notes

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