反应详情

A mixture of 1-[4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyrid-1-yl]-2-(6-methoxy-naphth-2-yl)ethane hydrochloride (0.6 g, 0.0013 mol) (obtained as described in Example 3) and 33% HBr in acetic acid (20 ml) is refluxed for 4 hours. The precipitate which forms is recovered by filtration and crystallised from 95% ethanol affording the compound indicated in the title (0.3 g) with m.p. 210°-212° C.

1. temperatureis refluxed for 4 hours
2. filtrationThe precipitate which forms is recovered by filtration
3. customcrystallised from 95% ethanol affording the compound