HCID 28413661, compound → HCID 58413332, compound

HRID 532295Notes

Reaction equation

HRID 532295 reaction equation
[NH2:1][C:2]1[C:3]([O:8][CH2:9][CH2:10][OH:11])=[N:4][CH:5]=[CH:6][CH:7]=1.[CH3:12][O:13][C:14]([C:16]1[S:25][C:19]2[N:20]=[C:21](Cl)[N:22]=[CH:23][C:18]=2[C:17]=1[CH3:26])=[O:15]>>[CH3:12][O:13][C:14]([C:16]1[S:25][C:19]2[N:20]=[CH:21][N:22]=[C:23]([NH:1][C:2]3[C:3]([O:8][CH2:9][CH2:10][OH:11])=[N:4][CH:5]=[CH:6][CH:7]=3)[C:18]=2[C:17]=1[CH3:26])=[O:15]

Participants

3

Reactant 2

HCID 28413661HCID 28413661, compoundHCID 82104641HCID 82104641, compound

Product 1

HCID 58413332HCID 58413332, compound

Procedure

Prepared analogously to example 28.1 from 2-(3-aminopyridin-2-yloxy)ethanol (175 mg) and chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylic acid methyl ester (121 mg)

Sources & evidence

ORD record
ord-56667ac90da14a54b115af2d2b04039c
Source dataset
uspto-grants-2014_10
Patent number
US08853193B2

Reaction notes

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