Ammonia → HCID 58413319, compound

HRID 532296Notes

Reaction equation

HRID 532296 reaction equation
[OH:1][CH2:2][CH2:3][O:4][C:5]1[C:10]([NH:11][C:12]2[C:13]3[C:20]([CH3:21])=[C:19]([C:22]([OH:24])=O)[S:18][C:14]=3[N:15]=[CH:16][N:17]=2)=[CH:9][CH:8]=[CH:7][N:6]=1.[NH3:25]>O1CCOCC1>[OH:1][CH2:2][CH2:3][O:4][C:5]1[C:10]([NH:11][C:12]2[C:13]3[C:20]([CH3:21])=[C:19]([C:22]([NH2:25])=[O:24])[S:18][C:14]=3[N:15]=[CH:16][N:17]=2)=[CH:9][CH:8]=[CH:7][N:6]=1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 58413300HCID 58413300, compound

Product 1

HCID 58413319HCID 58413319, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Prepared analogously to example 28.3 using 4-(2-(2-hydroxyethoxy)pyridin-3-ylamino)-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid (30.5 mg) and ammonia in dioxane (0.5M; 1.6 ml)

Sources & evidence

ORD record
ord-a0f4823263d840e29d19393670d474fe
Source dataset
uspto-grants-2014_10
Patent number
US08853193B2

Reaction notes

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