N,N-Dimethyl-1,3-propanediamine → HCID 46182085, compound

HRID 532305Notes

Reaction equation

HRID 532305 reaction equation
[CH:1]([O:4][C:5]1[C:10]([NH:11][C:12]2[C:13]3[C:20]([CH3:21])=[C:19]([C:22](O)=[O:23])[S:18][C:14]=3[N:15]=[CH:16][N:17]=2)=[CH:9][CH:8]=[CH:7][N:6]=1)([CH3:3])[CH3:2].[CH3:25][N:26]([CH3:31])[CH2:27][CH2:28][CH2:29][NH2:30]>>[CH3:25][N:26]([CH3:31])[CH2:27][CH2:28][CH2:29][NH:30][C:22]([C:19]1[S:18][C:14]2[N:15]=[CH:16][N:17]=[C:12]([NH:11][C:10]3[C:5]([O:4][CH:1]([CH3:3])[CH3:2])=[N:6][CH:7]=[CH:8][CH:9]=3)[C:13]=2[C:20]=1[CH3:21])=[O:23]

Participants

3

Reactant 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 46182084HCID 46182084, compound

Product 1

HCID 46182085HCID 46182085, compound

Procedure

Prepared analogously to example 1.3 using 4-(2-isopropoxypyridin-3-ylamino)-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid (descirbed in 1.2) and 3-dimethylaminopropylamine. The resultant product was purified by chromatography.

Workup

  1. customThe resultant product was purified by chromatography

Sources & evidence

ORD record
ord-9630b6c51d1e4f078ef86b5c12457e30
Source dataset
uspto-grants-2014_10
Patent number
US08853193B2

Reaction notes

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