反应详情

The product from 55 (170 mg) and TBTU (150 mg) was dissolved in ACN (5 ml). TEA (150 μl) was added to the mixture. The mixture was stirred for 15 min. at rt. Then tert-butyl N-(3-Aminopropyl)carbamate (200 mg) was added. The mixture was stirred at 50° C. for 2 days. Afterwards the mixture was diluted with water and filtrated. The solid was washed with water and dried in an oven

1. stirringThe mixture was stirred at 50° C. for 2 days
2. filtrationfiltrated
3. washThe solid was washed with water
4. customdried in an oven