HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyclopropylethynyl-3-nitrothiophene-2-carboxylic acid methyl ester → HCID 68937626, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyclopropylethynyl-3-nitrothiophene-2-carboxylic acid methyl ester | HCID 68942096 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68937626 | HCID 68937626 | — |
Reaction Steps
A suspension of 5-cyclopropylethynyl-3-nitrothiophene-2-carboxylic acid methyl ester (104 mg) and palladium (10% on carbon, 10 mg) in methanol (10 mL) was vigorously stirred under an atmosphere of hydrogen at atmospheric pressure for 5 hours. The catalyst was then filtered off with suction, and the filtrate was concentrated. The product with the molecular weight of 225.31 (C11H15NO2S); MS (ESI): 226 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853208B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-0a9f384e582e4c69af8eb2fc5f6e07ae |
| Source note | uspto-grants-2014_10 |