Tetrabutylammonium Fluoride → HCID 68941363, compound

Participants

Reaction Steps

A mixture of 6-(tert-butyldiphenylsilanyloxymethyl)-3-[4-(2-dimethylaminoethoxy)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one (1.6 g), tetra-N-butylammonium fluoride (3.2 mL) in THF (23 mL) was stirred at room temperature for 3 h. The solvent was removed in vacuo. The crude product was purified by preparative HPLC. The product with the molecular weight of 345.42 (C17H19N3O3S) was obtained in this way; MS (ESI): 346 (M+H+).

Provenance & Evidence