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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 532453Generated: October 30, 2026

Dimethylformamide dimethyl acetal → 5-Cyclopentanecarbonyl-3-(dimethylaminomethyleneamino)thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/532453

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamide dimethyl acetalHCID 78373—
Reactant3-Amino-5-cyclopentanecarbonylthiophene-2-carboxylic acid methyl esterHCID 68943556—
Product5-Cyclopentanecarbonyl-3-(dimethylaminomethyleneamino)thiophene-2-carboxylic acid methyl esterHCID 68945678—

Reaction Steps

3-Amino-5-cyclopentanecarbonylthiophene-2-carboxylic acid methyl ester and dimethoxymethyldimethylamine were reacted by method B. The product with the molecular weight of 308.40 (C15H20N2O3S) was obtained in this way; MS (ESI): 309 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853208B2
Source datasetuspto-grants-2014_10
ORD IDord-4aef1150a3a243c58094f5af7c441924
Source noteuspto-grants-2014_10