Dichloromethane → HCID 68299300, compound

Participants

Reaction Steps

50 mg of 7-(2-fluoro-4-methanesulfonyl-phenyl)-4-[piperidin-4-yloxy]thieno[3,2-d]pyrimidin was added to 1 ml of dichloromethane, and 32 μl of triethylamine was added thereto. 16 μl of (bromomethyl)benzene was added to the mixture, and after 1 hr, water was added thereto for terminating the reaction. The resulting solution was extracted with dichloromethane, dried over anhydrous sodium sulfate, and concentrated under a reduced pressure to obtain a bubble residue. The resulting residue was purified by column chromatography to obtain 30 mg of the title compound.

Provenance & Evidence