Hydrochloric Acid → HCID 71816007, compound

Participants

Reaction Conditions

Reaction Steps

6-(4′-Trifluoromethyl-biphenyl-4-yl)-4-(2-trimethylsilanyl-ethoxymeth yl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.14 g, 0.27 mmol) was dissolved in MeOH and treated with concentrated HCl (0.1 mL, 27 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 6-(4′-Trifluoromethyl-biphenyl-4-yl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.04 g, 0.1 mmol) as brown solid in 38% yield.

Provenance & Evidence