Acetic Acid → HCID 71816013, compound

Participants

Reaction Conditions

Reaction Steps

5-(Pyridine-4-carbonyl)-5,6-dihydro-cyclopenta[b]thiophen-4-one (1.95 g, 8 mmol), hydrazine monohydrate (0.6 mL, 12 mmol), glacial acetic acid (1.4 mL) and ethanol (20 mL) were heated at 100° C. under nitrogen for 4 hr. The mixture was cooled to 25° C. and concentrated under reduced pressure to give a solid which was recrystallized from ethanol to provide the corresponding 6-Pyridin-4-yl-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (1.16 g, 4.2 mmol) as white solid in 53% yield.

Provenance & Evidence