Hydrochloric Acid → HCID 71815171, compound

Participants

Reaction Conditions

Reaction Steps

2-Methoxy-4-[6-(4-methoxy-phenyl)-4-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalen-2-yl]-phenol (0.47 g, 0.9 mmol) was dissolved in MeOH and treated with concentrated HCl (0.3 mL, 9.03 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 2-Methoxy-4-[6-(4-methoxy-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalen-2-yl]-phenol (0.35 g, 0.76 mmol) as brown solid in 85% yield.

Provenance & Evidence