Hydrochloric Acid → HCID 71815238, compound

Participants

Reaction Conditions

Reaction Steps

6-[4-(4-Methyl-piperazin-1-yl)-phenyl]-4-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.22 g, 0.47 mmol) was dissolved in MeOH and treated with concentrated HCl (0.14 mL, 4.7 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 6-[4-(4-Methyl-piperazin-1-yl)-phenyl]-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.1 g, 0.35 mmol) as brown solid in 74% yield.

Provenance & Evidence