Hydrochloric Acid → HCID 71815306, compound

Participants

Reaction Conditions

Reaction Steps

6-(4-Pyrrolidin-1-yl-phenyl)-4-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (1.7 g, 0.38 mmol) was dissolved in MeOH and treated with concentrated HCl (0.12 mL, 3.8 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 6-(4-Pyrrolidin-1-yl-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.1 g, 0.3 mmol) as brown solid in 85% yield.

Provenance & Evidence